JailbreakMe.com these days is known as the domain you need to visit in order to jailbreak iPad 2 on iOS 4.3.3. Keep in mind though that JailbreakMe.com has been sold and all web-based jailbreaks, including that of iPad 2, have been shifted over to Jailbreaks.me.
JailbreakMe.com is particularly famous with amateur or new jailbreakers who do not know how to jailbreak using redsn0w, sn0wbreeze or pwnagetool. It was very easy to jailbreak your iOS device, as you just had to visit this website using Safari on the device you wanted to jailbreak and by tapping a button, your device would automatically be jailbroken untethered. JailbreakMe.com has hosted jailbreaks for various firmwares in the past but recently, JailbreakMe 3.0 was released which brought the anxiously awaited iPad 2 jailbreak, albeit on iOS 4.3.3.
Comex, the developer who released iPad 2 jailbreak, now works for Apple and has obviously mended his jailbreaking ways. The owners of JailbreakMe.com domain, Conceited Apps, have sold this domain due to the fact that Comex is not going to be working on JailbreakMe any more. They have owned this domain however they allowed Comex to host his jailbreak on this domain. It is obvious that JailbreakMe.com receives tons of traffic each day as literally millions of iOS devices have been jailbroken using it, so Conceited Apps is bound to have made a fortune off of it. The new owner to which it has been sold is said to be an unsafe and untrusted source who can use this popular domain to possibly spread iOS malware and cause harm to your devices.
However there's no reason to worry thinking that iPad 2 jailbreak will be lost for ever. MuscleNerd of the iPhone Dev Team has said via Twitter that since the jailbreak community will be looking after web based jailbreaks now they have shifted the jailbreaks over to the new Jailbreaks.me domain which, as he claims, will never be sold out to any one.
They are still in the process of setting it up but soon enough, you will be able to jailbreak iPad 2 on iOS 4.3.3 by simply pointing Safari on your iPad 2 to Jailbreaks.me. Since Comex's latest jailbreak was a PDF based exploit, all iOS devices running iOS 4.3.3 can be jailbroken by visiting this new URL.
For your own safety, we urge you to stay away from JailbreakMe.com as it may host iOS malware that might harm your device. Keep in mind that the correct URL now is Jailbreaks.me.